Partners involved: CNR-IFC, CNR-IN,UNIPI
Coordinators: Fabiola PAIAR (UNIPI), Eleonora VANNINI (CNR-IN)
Outline: The aim of this sub-project is to acquire preclinical data in vivo and to adapt the ElectronFlash LINAC for the clinical use to further explore the potential of EF, in a feasibility and safety study of FLASH-RT in patients with skin cancer. This perspective is of extraordinary interest since, beyond the pure dermatological application, the skin represents an organ at risk for radiotherapy in general and therefore a specific dermatological trial would offer relevant information for the progress of all clinical studies. Moreover, the combination of Flash-RT with chemotherapy, targeted therapy and immunotherapy will be investigated in pre-clinical tests.